Malegra contains sildenafil, which is used to treat erectile dysfunction (ED). Regarding taking it after meals: Yes, you can take Malegra after a meal. However, if you've had a large or high-fat meal (such as fried foods, pizza, or a heavy buffet), the medication may take longer to start working. For the fastest effect, many people take it on an empty stomach or after a light meal. It is typically taken 30–60 minutes before ***** activity. Do not take more than one dose in 24 hours. Avoid: Taking it with nitrate medications (such as nitroglycerin), because this can cause a dangerous drop in blood pressure. Drinking excessive amounts of alcohol, as this can increase dizziness and make it harder to get an erection. If you're asking about a specific strength (such as Malegra 50 mg or Malegra 100 mg) or how to take it with your other medications, let me know.