Tadfil 20 mg (tadalafil) with high cholesterol, you should consult a qualified healthcare professional. The safest options are:  Who Can Advise Primary Care Physician / Family Doctor Can review your overall health, medications, and cholesterol management. Will check for heart disease risk factors, which are important when taking ED medications. Cardiologist Especially recommended if you have high cholesterol with heart disease, angina, or blood pressure issues. Can assess cardiovascular safety for tadalafil, since ED drugs affect blood flow and blood pressure. Urologist / Men’s Health Specialist Can evaluate the appropriate ED medication and dose. Will consider interactions with cholesterol-lowering drugs (like statins).  Important Considerations Tadalafil is generally safe with statins, but your doctor will check for drug interactions and cardiovascular risk. High cholesterol often increases the risk of heart disease, so heart evaluation may be needed before starting any PDE5 inhibitor. Do not self-medicate, especially if you have heart disease, high blood pressure, or are on multiple medications.  A cardiologist or primary care doctor is the best person to advise on using Tadfil 20 mg safely with high cholesterol. They can determine dose, timing, and monitoring to reduce any risks.