If Malegra contains sildenafil (as most Malegra products do), it may be appropriate for adult men with erectile dysfunction, but it isn't safe for everyone. Generally suitable: adults with ED who have been assessed as healthy enough for ***** activity and who aren't taking interacting medicines. Do NOT take it if you: Use nitrate medicines such as nitroglycerin or isosorbide—this can cause a dangerous blood-pressure drop. D DailyMed Take riociguat. D DailyMed Have been advised to avoid ***** activity because of a serious cardiovascular condition. D DailyMed Have had an allergic reaction to sildenafil. Extra caution/dose adjustment may be needed with alpha-blockers, some blood-pressure medicines, certain antibiotics/antifungals or HIV medicines, and with significant kidney or liver disease. D DailyMed +1 Also, don't combine Malegra with Fildena, Cenforce, Vilitra, Tadalista, or another ED medicine unless a doctor specifically instructs you. If you tell me your age, Malegra strength (e.g. 50/100 mg), and the medicines you take, I can tell you whether there are any specific safety concerns.