Malegra DXT may be safe for some adults when prescribed appropriately, but it depends on its exact ingredients and your health history. Products sold under the Malegra DXT name commonly contain sildenafil plus dapoxetine, combining ED treatment with treatment for premature *****. Key safety points: Sildenafil can cause headache, flushing, indigestion, dizziness, and vision changes. Do not use sildenafil with nitrate medicines or riociguat because blood pressure can fall dangerously. Combining sildenafil with other PDE5 inhibitors or ED medicines is not recommended. People with certain cardiovascular conditions should be medically assessed before using ED medicines. Seek emergency care for an erection lasting more than 4 hours. Because Malegra DXT is a combination product, its safety also depends on the dapoxetine component and any medicines you take. A doctor or pharmacist should check the full medication list before you use it.