Tadalista must not be taken with nitrates. Tadalista contains tadalafil, and combining it with nitrate medicines can cause a sudden, dangerous drop in blood pressure, potentially leading to fainting, a heart attack, or a stroke. DailyMed +1 Which medicines are nitrates? Examples include: Nitroglycerin (GTN): tablets, sprays, patches, or other forms used for angina (chest pain). Isosorbide mononitrate Isosorbide dinitrate Recreational nitrites sometimes called poppers. How long should you wait after Tadalista? At least 48 hours must pass after your last tadalafil dose before nitrates may even be considered in a medical emergency. After those 48 hours, nitrates should only be administered under close medical supervision if necessary. Do not use this waiting period as permission to restart nitrates yourself. DailyMed +1 If you have taken Tadalista and develop chest pain, seek emergency medical help. Do not take nitroglycerin yourself, and tell emergency personnel when you last took tadalafil. To help clarify your situation: Are you currently taking a nitrate for a heart condition, or are you asking because you occasionally use Tadalista for erectile dysfunction?