Cenforce 130 mg can interact with heart medications, potentially causing a dangerous drop in blood pressure. Cenforce 130 mg is marketed as sildenafil 130 mg, a dose higher than the usual maximum recommended dose of 100 mg for erectile dysfunction. New 200 Products for Insta +1 Which heart medicines are a concern? Nitrates — never combine: Nitroglycerin and isosorbide medicines can cause a life-threatening drop in blood pressure when taken with sildenafil. Alpha-blockers: Doxazosin and similar medicines can increase dizziness and fainting. Blood pressure medicines: Amlodipine, beta-blockers and other antihypertensives may further lower blood pressure. Riociguat: Must not be combined with sildenafil. DailyMed +1 What should you do? Do not take Cenforce 130 mg until a doctor or pharmacist has reviewed your heart condition and medications. If you develop chest pain after taking sildenafil, seek emergency medical care and tell the medical team you took sildenafil; do not take nitroglycerin yourself. One important question Which heart or blood pressure medicine are you taking? For example, amlodipine, telmisartan, atenolol, aspirin, or nitroglycerin. I can explain the specific interaction and precautions.