Malegra FXT Plus can generally be taken with food, because its sildenafil component can be taken with or without food. D DailyMed +1 However, there is an important difference: Normal/light meal: generally fine.  Heavy or high-fat meal: may make sildenafil take longer to work. A high-fat meal has been shown to delay absorption by about 60 minutes and reduce peak blood levels by about  If you're using it for planned ***** activity, taking it without a heavy meal may give a more predictable onset. Also, because FXT Plus contains another active ingredient in addition to sildenafil, the exact formulation matters. If you tell me the strength printed on your Malegra FXT Plus strip (e.g., sildenafil ___ mg + fluoxetine ___ mg), I can tell you the best way to take that specific version.