Malegra 100 mg (contains sildenafil 100 mg) should be avoided or used only under strict medical supervision in diabetic patients in certain situations, especially when diabetes has led to complications or when other risk factors are present. When diabetics should avoid it 1. If taking nitrate heart medicines Such as nitroglycerin, isosorbide, etc. Can cause a dangerous drop in blood pressure This is an absolute contraindication 2. If diabetes has caused severe heart disease History of heart attack, unstable angina, or recent cardiac event ***** activity itself may already be risky in these cases 3. If blood pressure is very low or uncontrolled Diabetics with autonomic neuropathy may have unstable BP Sildenafil can worsen dizziness or fainting 4. Severe liver or kidney disease due to diabetes Poor drug clearance increases side effects risk 5. Recent stroke or serious vascular complications Diabetes increases vascular risk; sildenafil may add stress in unstable conditions 6. When taking interacting medicines Alpha-blockers (for prostate/BP) without dose adjustment Certain antifungals, antibiotics, or HIV medicines that increase sildenafil levels .